fosaprepitant will enhance the degree or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.Monitor Intently (one)mitotane decreases levels of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Mitotane is a powerful inducer of cytochrome P-4503A4; monitor wh